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Vyvanse (lisdexamfetamine) is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.

Vyvanse is FDA-approved to treat attention deficit hyperactivity disorder (ADHD) in adults and in children who are at least 6 years old.

Vyvanse is also used to treat moderate to severe binge eating disorder in adults. This medicine is not to be used for obesity or weight loss.

MORE ABOUT VYVANSE

What is VYVANSE and how is it used?

VYVANSE is a central nervous system stimulant prescription medicine used to treat: Attention-Deficit/Hyperactivity Disorder (ADHD). VYVANSE may help increase attention and decrease impulsiveness and hyperactivity in patients with ADHD. Binge Eating Disorder (BED). VYVANSE may help reduce the number of binge eating days in patients with BED. VYVANSE is not for weight loss. It is not known if VYVANSE is safe and effective for the treatment of obesity. It is not known if VYVANSE is safe and effective in children with ADHD under 6 years of age or in patients with BED under 18 years of age.

 

MAOI antidepressants slow amphetamine metabolism, increasing amphetamines effect on the release of norepinephrine and other monoamines from adrenergic nerve endings causing headaches and other signs of hypertensive crisis. Toxic neurological effects and malignant hyperpyrexia can occur, sometimes with fatal results.

Intervention

Do not administer VYVANSE during or within 14 days following the administration of MAOI [see CONTRAINDICATIONS].

Examples

selegiline, isocarboxazid, phenelzine, tranylcypromine

Clinical Impact

The concomitant use of VYVANSE and serotonergic drugs increases the risk of serotonin syndrome.

Intervention

Initiate with lower doses and monitor patients for signs and symptoms of serotonin syndrome, particularly during VYVANSE initiation or dosage increase. If serotonin syndrome occurs, discontinue VYVANSE and the concomitant serotonergic drug(s) [see WARNINGS AND PRECAUTIONS].

 

The following adverse reactions are discussed in greater detail in other sections of the labeling:

 

  • Known hypersensitivity to amphetamine products or other ingredients of VYVANSE
  • Hypertensive Crisis When Used Concomitantly with Monoamine Oxidase Inhibitors
  • Drug Dependence
  • Serious Cardiovascular Reactions
  • Blood Pressure and Heart Rate Increases
  • Psychiatric Adverse Reactions
  • Suppression of Growth
  • Peripheral Vasculopathy, including Raynaud’s
  • Serotonin Syndrome

Clinical Trial Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

INDICATIONS

VYVANSE® is indicated for the treatment of:

Attention Deficit Hyperactivity Disorder (ADHD) [see Clinical Studies]

Moderate to Severe Binge Eating Disorder (BED) in adults 

Limitation Of Use

VYVANSE is not indicated or recommended for weight loss.

Use of other sympathomimetic drugs for weight loss has been associated with serious cardiovascular adverse events.

The safety and effectiveness of VYVANSE for the treatment of obesity have not been established 

DOSAGE AND ADMINISTRATION

Pre-Treatment Screening

Prior to treating children, adolescents, and adults with CNS stimulants, including VYVANSE, assess for the presence of cardiac disease (e.g., a careful history, family history of sudden death or ventricular arrhythmia, and physical exam). Buy Vyvanse Online.

To reduce the abuse of CNS stimulants including VYVANSE, assess the risk of abuse, prior to prescribing. After prescribing, keep careful prescription records, educate patients about abuse, monitor for signs of abuse and overdose, and re-evaluate the need for VYVANSE use.

 

 

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Information For VYVANSE Capsules:

Swallow VYVANSE capsules whole, or

Open capsules, empty and mix the entire contents with yogurt, water, or orange juice. If the contents of the capsule include any compacted powder, a spoon may be used to break apart the powder.

The contents should be mixed until completely dispersed. Consume the entire mixture immediately.

It should not be stored. The active ingredient dissolves completely once dispersed; however, a film containing the inactive ingredients may remain in the glass or container once the mixture is consumed. Buy Vyvanse Online

Information For VYVANSE Chewable Tablets:

VYVANSE chewable tablets must be chewed thoroughly before swallowing.

VYVANSE capsules can be substituted with VYVANSE chewable tablets on a unit per unit/ mg per mg basis (for example, 30 mg capsules for 30 mg chewable tablet)

Do not take anything less than one capsule or chewable tablet per day. A single dose should not be divided.

Information For VYVANSE Chewable Tablets:

Dosage For Treatment Of ADHD

The recommended starting dose is 30 mg once daily in the morning in patients ages 6 and above. Dosage may be adjusted in increments of 10 mg or 20 mg at approximately weekly intervals up to maximum dose of 70 mg/day. 

Dosage For Treatment Of Moderate To Severe BED In Adults

The recommended starting dose is 30 mg/day to be titrated in increments of 20 mg at approximately weekly intervals to achieve the recommended target dose of 50 to 70 mg/day. The maximum dose is 70 mg/day [see Clinical Studies]. Discontinue VYVANSE if binge eating does not improve.

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ADHD SOSAGE

Follow all directions on your prescription label. Your doctor may occasionally change your dose.

Do not take dextroamphetamine in larger or smaller amounts or for longer than recommended.

Dextroamphetamine may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. 

Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

Dextroamphetamine is sometimes taken 2 or 3 times per day. Extended-release dextroamphetamine is taken only once per day.

Follow your doctor’s dosing instructions very carefully.

 

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of dextroamphetamine can be fatal.

Overdose symptoms may include restlessness, tremor, muscle twitches, rapid breathing, confusion, hallucinations, panic, aggressiveness, muscle pain or weakness, and dark colored urine.

These symptoms may be followed by depression and tiredness. Other overdose symptoms include nausea, vomiting, diarrhea, stomach pain, uneven heartbeats, feeling light-headed, fainting, seizure (convulsions), or coma.

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